Our Publications

• Musa J, Kochendoerfer SM, Willis F, Sauerteig C, Harnoss JM, Rompen IF, Grünewald TGP, Al-Saeedi M, Schneider M, Harnoss JC. The GIST of it all: management of gastrointestinal stromal tumors (GIST) from the first steps to tailored therapy. A bibliometric analysis. Langenbecks Arch Surg. 2024 Mar 14;409(1):95. Impact factor: 2.7.


• Musa J, Willis F, Harnoss JM, Rompen IF, Sauerteig C, Kochendoerfer SM, Grünewald TGP, Al-Saeedi M, Schneider M, Harnoss JC. A century of retroperitoneal soft-tissue sarcoma research: From single center experience to precision oncology? A bibliometric analysis of past, present, and future perspectives. Eur J Surg Oncol. 2023 Jun 1:S0748-7983(23)00518-8. Impact factor: 4.533.


Kennel KB, Burmeister J, Radhakrishnan P, Giese NA, Giese T, Salfenmoser M, Gebhardt JM, Strowitzki MJ, Taylor CT, Wielockx B, Schneider M, Harnoss JM. The HIF-prolyl hydroxylases have distinct and non-redundant roles in colitis-associated cancer. JCI Insight 2022;7(22). Impact factor 9.484.


Harnoss JM, Cai J, Hinterkopf S, Radhakrishnan P, Schmitt A, Dupovac M, Nees LK, Strowitzki MJ, Taylor CT, Schneider M. Hydroxylase Inhibition Mitigates Allograft Injury During Liver Transplantation. Transplantation 2022 Oct 1;106(10):e430-e440. Impact factor 5.385.


• Biller ML, Tuffs C, Bleul M, Tran DT, Dupovac M, Keppler U, Harnoss JM, Probst P, Schneider M, Strowitzki MJ. Effect of Metformin on HIF-1α Signaling and Postoperative Adhesion Formation. J Am Coll Surg. 2022 Jun 1;234(6):1167-1180. Impact factor: 6.532.


• Guttman O, Le Thomas A, Marsters S, Lawrence DA, Gutgesell L, Zuazo-Gaztelu I, Harnoss JM, Haag SM, Murthy A, Strasser G, Modrusan Z, Wu T, Mellman I, Ashkenazi A. Antigen-derived peptides engage the ER stress sensor IRE1a to curb dendritic cross-presentation. J Cell Biol 2022 Jun 6;221(6):e202111068. Impact factor: 10.539.


• Le Thomas A, Ferri E, Marsters SA, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A. Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress  ensor IRE1a. Nat Comm. 2021 Dec 15;12(1):7310. Impact factor: 14.919


• Strowitzki MJ, Kimmer G, Wehrmann J, Ritter AS, Radhakrishnan P, Opitz VM, Tuffs C, Biller M, Kugler J, Keppler U, Harnoss JM, Klose J, Schmidt T, Blanco A, Taylor CT, Schneider M. Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses. JCI Insight. 2021 Mar 30;6(8):139191. Impact factor: 8.315.


Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. IRE1a disruption in triple-negative breast cancer cooperates with anti-angiogenic therapy by reversing ER stress adaptation and remodeling the tumor microenvironment. Cancer Res. 2020 Jun 1;80(11):2368-2379. Impact factor: 13.312


Harnoss JM, Gebhardt JM, Radhakrishnan P, Leowardi C, Burmeister J, Halligan DN, Yuan S, Kennel KB, Strowitzki MJ, Schaible A, Lasitschka F, Taylor CT, Schneider M. Prolyl Hydroxylase Inhibition Mitigates Pouchitis. Inflamm Bowel Dis. 2020 Jan 6;26(2):192-205. Impact factor: 4.261.


Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. Disruption of IRE1a through its kinase domain attenuates multiple myeloma. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16420-16429. Impact factor: 12.779.


• Shemorry A, Harnoss JM, Guttman O, Marsters SA, Kőműves LG, Lawrence DA, Ashkenazi A. Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress. Elife. 2019 Aug 27;8. pii: e47084. Impact factor: 6.830.


• Strowitzki MJ, Radhakrishnan P, Pavicevic S, Scheer J, Kimmer G, Ritter AS, Tuffs C, Volz C, Vondran F, Harnoss JM, Klose J, Schmidt T, Schneider M. High hepatic expression of PDK4 improves survival upon multimodel treatment of colorectal liver metastases. Br J Cancer. 2019 Apr;120(7):675-688. Impact factor: 5.490.


• Strowitzki MJ, Kirchberg J, Tuffs C, Schiedeck M, Ritter AS, Biller M, Harnoss JM, Lasitschka F, Schmidt T, Radhakrishnan P, Ulrich A, Schneider M. Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells. Am J Pathol. 2018 Dec;188(12):2826-2838. Impact factor: 3.710.


• Chang TK, Lawrence DA, Lu M, Tan J, Harnoss JM, Marsters SA, Liu P, Sandoval W, Martin SE, Ashkenazi A. Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate. Mol Cell. 2018 Aug 16;71(4):629-636.e5. Impact factor: 11.890.


• Krackhardt F, Harnoss JM, Waliszewski MW, Ritter Z, Granzow S, Felsenberg D, Neumann K, Lerman LO, Hillmeister P, Gebker R, Paetsch I, Riediger F, Bramlage P, Buschmann IR. Insights into coronary collateral formation from a novel porcine semiacute infarction model. Coron Artery Dis. 2018 Mar;29(2):127-137. Impact factor: 1.335.


Harnoss JM, Krackhardt F, Ritter Z, Granzow S, Felsenberg D, Neumann K, Lerman LO, Riediger F, Hillmeister P, Bramlage P, Buschmann IR. Porcine arteriogenesis is based on vasa vasorum in a novel semi-acute occlusion model using high-resolution imaging. Heart Vessels. 2017 Nov;32(11):1400-1409. Impact factor: 1.618.


• Strowitzki MJ, Ritter AS, Radhakrishnan P, Harnoss JM, Opitz VM, Biller M, Wehrmann J, Keppler U, Scheer J, Wallwiener M, Schmidt T, Ulrich A, Schneider M. Pharmacological HIF-inhibition attenuates postoperative adhesion formation. Sci Rep. 2017 Oct 13;7(1):13151. Impact factor: 3.998.


• Harnoss JC, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss JM, Ulrich A, Büchler MW, Diener MK. Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials (PROSPERO 2015:CRD42015016882). Ann Surg. 2017 May;265(5):889-900. Impact factor: 10.130.


Harnoss JM, Platzer LK, Burhenne J, Radhakrishnan P, Cai J, Strowitzki MJ, Weiss J, Ritter AS, Mollenhauer M, Schmidt T, Ulrich A, Haefeli WE, Schneider M. Prolyl Hydroxylase Inhibition Enhances Liver Regeneration Without Induction of Tumor Growth. Ann Surg. 2017 Apr;265(4):782-791. Impact factor: 13.787.


• de Sousa e Melo F, Kurtova AV, Harnoss JM, Kljavin N, Hoeck JD, Hung J, Anderson JE, Storm EE, Modrusan Z, Koeppen H, Dijkgraaf GJ, Piskol R, de Sauvage FJ. A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer. Nature. 2017 Mar 29;543(7647):676-680. Impact factor: 42.778.


• Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Hydroylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-b1 signaling. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. Impact factor: 3.760.


• Radhakrishnan P, Ruh N, Harnoss JM, Kiss J, Mollenhauer M, Scherr AL, Platzer LK, Schmidt T, Podar K, Opferman JT, Weitz J, Schulze-Bergkamen H, Koehler BC, Ulrich A, Schneider M. Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. Cancer Res. 2016 Apr 15;76(8):2219-30. Impact factor: 9.727.


• Leowardi C, Schneider ML, Hinz U, Harnoss JM, Tarantino I, Lasitschka F, Ulrich A, Büchler MW, Kadmon M. Prognosis of Ulcerative Colitis-Associated Colorectal Carcinoma Compared to Sporadic Colorectal Carcinoma: A Matched Pair Analysis. Ann Surg Oncol. 2016 Mar;23(3):870-6. Impact factor: 4.061.


Harnoss JM, Harnoss JC, Diener MK, Contin P, Ulrich AB, Büchler MW, Schmitz-Winnenthal FH. Portal annular pancreas: a systematic review of a clinical challenge. Portal annular pancreas: a systematic review of a clinical challenge. Pancreas. 2014 Oct;43(7):981-6. Impact factor: 2.920.


• Harnoss JC, Ulrich AB, Harnoss JM, Diener MK, Büchler MW, Welsch T. Use and results of consensus definitions in pancreatic surgery: a systematic review. Surgery. 2014 Jan;155(1):47-57. Epub 2013 Oct 25. Impact factor: 3.356.


Harnoss JM, Yung R, Brodsky RA, Hruban RH, Boitnott JK, Murphy DJ, Yang SC, Choti MA. Bronchobiliary fistula and lithoptysis after endoscopic retrograde cholangiopancreatography and liver biopsy in a patient with paroxysmal nocturnal hemoglobinuria. Am J Respir Crit Care Med. 2013 Feb 15;187(4):451-4. Impact factor: 16.494.